This composition contains paracetamol, Phenylepinephrine and cetirizine which is used in the treatment of symptoms of common cold and allergic reactions.
Its bocks the release of histamine i.e. chemical messenger and thus reduces pain and fever. It prevents the congestion or stiffness of nose by preventing narrowing of blood vessels.
It is used to lowers the increased or elevated level of temperature of the blood.
Seasonal allergic rhinitis
Perennial allergic rhinitis
Chronic urticaria
Headache
Fever
Paracetamol-
It is over the counter medication and is used in to provide relive against cold, fever and for providing relief. It is available in various strengths for different age groups.
Phenylepinephrine-
Phenylepinephrine binds with the beta-1 adrenergic receptor agonist and induces vasoconstriction or is used to treat vasodilation and mediates hypotension.
Cetirizine-
Cetirizine belongs to first generation antihistaminic and has no sedative action.
Cetirizine relieves the symptoms of allergic reactions such as running nose, watery eyes, sneezing, hives, Itching.
Paracetamol blocks the cyclooxygenase enzyme which is necessary for the production of prostaglandins.
Phenylephrinebinds to the adrenergic receptors and thus prevents the vasoconstriction because they mimic the activity of Phenylepinephrine.
Cetirizine binds to the peripheral H1 receptor and inhibit their activity.
Conjunctivitis
Headache
Fatigue
Blurred vision
Rashes
Constipation
Dry mouth
Dizziness
Contraindicated in people with known hypersensitivity
Contraindicated in liver disorders
Warfarin
MOA-inhibitors
| Paracetamol IP | 500 mg |
| Phenylephrine IP | 5 mg |
| Cetirizine HCL IP | 5 mg |