Cefuroxime Axetil is a prescription medicine used alone or with other medications to treat the symptoms of bacterial infections. Ceftin is a cephalosporin antibiotic and it is not known if it is safe and effective in children younger than 3 months of age. It is a semisynthetic, cephalosporin antibacterial drug for oral administration.
Pharyngitis/Tonsillitis
Acute Bacterial Otitis Media
Acute Bacterial Maxillary Sinusitis
Acute Bacterial Exacerbations of Chronic Bronchitis
Uncomplicated Skin and Skin-structure Infections
Uncomplicated Urinary Tract Infections
Uncomplicated Gonorrhea
Early Lyme Disease (erythema migrans)
Cefuroxime axetil is a 2nd generation cephalosporin similar to penicillins antibiotics, containing a β-lactam ring structure. Cephalosporins acts as a bactericidal antibiotic which binds to penicillin-binding proteins, inhibiting the last step of the bacterial cell wall synthesis. Once the β-lactam ring binds to penicillin-binding proteins, cross-linking between peptidoglycan units is inhibited.
Absorption: After consumption, cefuroxime axetil is converted into active compound cefuroxime by esterases of mucosal cells in the gastrointestinal tract. Cefuroxime is then released for systematic circulation. Absorption of cefuroxime axetil increases by 52% when given with food as compared to fasting patients.
Distribution: After cefuroxime axetil administration, it can be found in tonsil tissue, bronchial tissue, sinus tissue and middle ear effusion.
Elimination: once cefuroxime is produced the body is unable to metabolize the drug which is then eliminated unchanged in the urine.
Diarrhea
Nausea
Vomiting
Severe stomach pain
Yellowing of skin or the eyes
Skin rash
Bruising
Consult your physician if you are allergic to it or to penicillins or other cephalosporin antibiotics (e.g., cephalexin); or if you have any other allergies.
This drug may make you dizzy or drowsy. Consumption of alcohol or marijuana can make you even more dizzy or drowsy.
Avoid driving, using machinery, or doing anything that needs alertness until you can do it safely.
Elderly patients are more sensitive to this drug, therefore caution is required while administration.
This medication passes into breast milk. Consult your doctor before breast-feeding.
Contraindicated in patients with known allergy to the cephalosporin group of antibiotics.
| Cefuroxime Axetil | 250 mg |