This composition contains Omeprazole and domperidone which is used to treat chronic gastritis and controls the emesis, gastric emptying. They also provide relief from helicobacter infections.
Peptic ulcer
Gastroesophageal reflux disease
Omeprazole inhibits the H+K+ATPase pump present on the surface of parietal cell and thus inhibit the gastric acid secretion.
Domperidone acts on the D1 and D2 receptors and blocks its activity. domperidone increases gastric emptying and decreases bowel transit through peristalsis.
Omeprazole-
It is absorbed orally
It is 95% bound to plasma proteins
It is metabolized in the liver
It is excreted via urine
Diarrhoea
Stomach pain
Dryness of mouth
Headache
Flatulence
Contraindicated in patients with known hypersensitivity
Chlorpromazine
Pimozide
Arsenic trioxide
Ondansetron
Probucol
| Omeprazole HCL | 20 mg |
| Domperidone HCL | 10 mg |