For relief of mild to moderate pain.
Pain and fever due to upper respiratory tract infections.
Spondylitis.
Back and Joint Pain.
Headache

Aceclofenac is rapidly and completely absorbed from GIT. Time to reach maximum concentration in plasma is about 1.23-3 hours. It is highly bound protein drug with 99% and the volume of distribution is about 25 L. It is metabolised by CYP enzyme family and 70-80% of the metabolites are excreted in urine with only 20% excreted in feces. The half-life is approximately 4 hours.

Paracetamol is also well orally absorbed and volume of distribution is 1.29 l/kg. Protein binding of paracetamol is very negligible. It is metabolised in liver mainly by CYP enzymes. Paracetamol is mainly excreted in urine with a half-life of 3.6 hours.

Serratiopeptidase is absorbed through the intestines and transported directlyinto the bloodstream. But being a peptide there would be a high propensity of this enzyme to undergo enzymatic degradation in the gastrointestinal tract and low membrane permeability due to the hydrophilic nature of peptides and proteins in general.44,45 So these factors could lead to low bioavailability of this enzyme when used therapeutically. It was seen that the peak concentration in plasma and lymph at a dose of 100 mg/kg were 0.87 0.41 and 43 42 ng/ml, respectively, and this peak plasma concentration was achieved 0.25e0.5 h after the dose and disappeared by 6 h.

Do not use paracetamol in the following conditions:
Caloric undernutrition.
Severe renal impairment.
A condition where the body is unable to maintain adequate blood flow called shock.
Acetaminophen overdose.
Acute inflammation of the liver due to hepatitis C virus.